When your stomach makes too much acid, it can burn your esophagus, cause chronic heartburn, or even lead to ulcers. That’s where acid reduction therapy, a medical approach to lowering stomach acid production to relieve symptoms and heal damage. Also known as anti-reflux therapy, it’s one of the most common treatments for people with GERD, peptic ulcers, or chronic indigestion. This isn’t just about popping antacids before bed—it’s a targeted strategy using medications that block acid at its source.
Two main types of drugs drive this therapy: proton pump inhibitors, medications that shut down the stomach’s acid-producing pumps. Also known as PPIs, they include omeprazole, esomeprazole, and lansoprazole. And then there are H2 blockers, drugs that reduce acid by blocking histamine receptors in the stomach lining. Also known as histamine-2 receptor antagonists, these include ranitidine and famotidine. PPIs are stronger and longer-lasting, often used for healing damage. H2 blockers work faster but don’t last as long—great for quick relief or nighttime use. Both are widely prescribed, but they’re not interchangeable. Choosing the right one depends on your symptoms, how long you’ve had them, and whether you’ve tried other options.
Acid reduction therapy isn’t just about comfort. Left untreated, excess acid can cause esophagitis, Barrett’s esophagus, or even increase cancer risk over time. It also interacts with other meds—some antibiotics, blood thinners, and bone drugs work differently when acid levels drop. That’s why knowing how and when to use these drugs matters. You don’t need to take them forever, but stopping too soon can bring symptoms back harder. Many people use them short-term to heal, then switch to lifestyle changes or lower doses.
The posts below cover real-world issues tied to acid reduction therapy: how to take these meds safely, what happens when they don’t work, how they affect other conditions, and what alternatives exist for people who can’t tolerate them. You’ll find comparisons between common drugs, tips for avoiding side effects, and insights into how long-term use might impact your body. Whether you’re just starting treatment or have been on it for years, this collection gives you clear, practical info—not guesswork.